{"product_id":"afinitor-everolimus","title":"AFINITOR (Everolimus)","description":"\u003ch5\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cb\u003eAFINITOR (Everolimus)\u003cbr\u003e\u003c\/b\u003e\u003cspan\u003eAntineoplastic Agent; mTOR Kinase Inhibitor\u003c\/span\u003e\u003cspan\u003e; \u003c\/span\u003e\u003cspan\u003eImmunosuppressant Agent\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAFINITOR (Everolimus) is indicated for the treatment of advanced b\u003c\/span\u003ereast cancer, neuroendocrine tumors (GI, lung, or pancreatic origin), advanced renal cell carcinoma, and tuberous sclerosis complex-associated renal angiomyolipoma.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eALERT: WARNING\u003cbr\u003e\u003c\/b\u003eBreast cancer; Neuroendocrine tumors; Renal cell carcinoma; Tuberous sclerosis complex-associated renal angiomyolipoma \u003ci data-mce-fragment=\"1\"\u003e(AFINITOR ONLY)\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTuberous sclerosis complex-associated partial-onset seizures \u003ci data-mce-fragment=\"1\"\u003e(AFINITOR DISPERZ ONLY)\u003c\/i\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTuberous sclerosis complex-associated subependymal giant cell astrocytoma \u003ci data-mce-fragment=\"1\"\u003e(AFINITOR or AFINITOR DISPERZ)\u003c\/i\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eAFINITOR (Everolimus) is a macrolide immunosuppressant and a mechanistic target of rapamycin (mTOR) inhibitor which has antiproliferative and antiangiogenic properties.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eAFINITOR:\u003c\/strong\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003cbr\u003eOral:\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\"\u003e Take 10 mg once daily until disease progression or unacceptable toxicity.\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/i\u003e\u003cstrong\u003eAFINITOR DISPERZ: \u003c\/strong\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cbr\u003eOral: \u003c\/span\u003e\u003c\/i\u003eTake\u003cspan data-mce-fragment=\"1\"\u003e 4.5 or 5 mg\/m\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e2\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e once daily until disease progression or unacceptable toxicity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHow to Take:\u003c\/b\u003e\u003cspan\u003e \u003cbr\u003e\u003cem\u003eAfinitor:\u003c\/em\u003e Swallow whole with a glass of water. May be taken with or without food, but to reduce variability take consistently with regard to food. Administer at the same time(s) each day. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eAfinitor Disperz: \u003c\/em\u003eAdminister as a suspension only. Administer immediately after preparation, discard if not administered within 60 minutes after preparation. Prepare suspension in water only. Do not break or crush tablets.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat should I watch for while using this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBefore starting AFINITOR (Everolimus) make sure your physician is aware of any allergies or medications you currently take, if you have experienced any of the following medical conditions: solid organ transplant, hepatic impairment, hereditary galactose intolerance, and renal impairment.  Everolimus use has been associated with rare but serious adverse events such as non-infectious pneumonitis which requires monitoring for signs and symptoms.  Other serious adverse effects include oral ulcers, stomatitis, bone marrow suppression, edema, graft thrombosis, hepatic artery thrombosis, hypersensitivity reactions, malignancy, metabolic effects, mucositis, nephrotoxicity, pulmonary toxicity and renal failure.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIf you miss a dose of AFINITOR (Everolimus), you may still take it up to 6 hours after the time you normally take it. If it is more than 6 hours after you normally take your dose, skip the dose for that day. The next day, Everolimus at your usual time. Do not take 2 doses to make up for the one that you missed. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003eStore at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light and moisture. Store in the original container.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eStomatitis, sinusitis, infections, otitis media,  asthenia, fatigue, cough, and diarrhea.  \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003cspan\u003eNote this is not a complete list of side effects for AFINITOR (Everolimus), only common ones.\u003c\/span\u003e\u003c\/p\u003e","brand":"NOVARTIS PHARMACEUTICALS","offers":[{"title":"2.5mg - 30 Tab - Canada","offer_id":47130317193534,"sku":null,"price":11900.0,"currency_code":"USD","in_stock":true},{"title":"2.5mg - 30 Tab - Australia","offer_id":47130317226302,"sku":null,"price":11900.0,"currency_code":"USD","in_stock":true},{"title":"5mg - 30 Tab - Canada","offer_id":47130317259070,"sku":null,"price":12460.0,"currency_code":"USD","in_stock":true},{"title":"5mg - 30 Tab - Australia","offer_id":47130317291838,"sku":null,"price":12460.0,"currency_code":"USD","in_stock":true},{"title":"10mg - 30 Tab - Canada","offer_id":47130317324606,"sku":null,"price":13380.0,"currency_code":"USD","in_stock":true},{"title":"10mg - 30 Tab - Australia","offer_id":47130317357374,"sku":null,"price":13380.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/products\/Afinitor2.5mg.jpg?v=1695114794","url":"https:\/\/www.advochealth.com\/products\/afinitor-everolimus","provider":"AdvocHealth","version":"1.0","type":"link"}