{"product_id":"apremilast-apremilast","title":"APREMILAST (Apremilast)","description":"\u003ch5\u003eWhat is this medication?\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eApremilast\u003c\/strong\u003e is a phosphodiesterase 4 (PDE4) inhibitor that works to suppress the immune system, which reduces inflammation. \u003cstrong\u003eApremilast\u003c\/strong\u003e is used to treat active psoriatic arthritis in adults.\u003cstrong\u003eApremilast\u003c\/strong\u003e is also used to treat moderate to severe plaque psoriasis in adults who may also receive phototherapy or other treatments for psoriasis.\n\u003cstrong\u003eApremilast\u003c\/strong\u003e is also used to treat mouth ulcers in adults with Behçet's disease (a disease causing inflammation in blood vessels).\u003c\/p\u003e\n\u003ch5\u003eHow should I take this medication?\u003c\/h5\u003e\nTake apremilast exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. You may take apremilast with or without food. Swallow the tablet whole and do not crush, chew, or break it. Keep track of your body weight while you are taking this medicine, and tell your doctor about any major weight loss.\n\u003cstrong\u003eDosing information\u003c\/strong\u003e Usual Adult Dose for Psoriatic Arthritis:\nInitial dose:\n\n\u003cul\u003e\n\u003cli\u003eDay 1: 10 mg orally once a day (AM)\u003c\/li\u003e\n\u003cli\u003eDay 2: 10 mg orally twice a day (AM and PM)\u003c\/li\u003e\n\u003cli\u003eDay 3: 10 mg orally once a day (AM); 20 mg orally once a day (PM)\u003c\/li\u003e\n\u003cli\u003eDay 4: 20 mg orally twice a day (AM and PM)\u003c\/li\u003e\n\u003cli\u003eDay 5: 20 mg orally once a day (AM); 30 mg orally once a day (PM)\u003c\/li\u003e\n\u003c\/ul\u003e\nMaintenance dose: 30 mg orally twice a day (AM and PM)\nComments: This titration is intended to reduce the gastrointestinal symptoms associated with initial therapy.\nUse: Treatment of adult patients with active psoriatic arthritis.\n\n\u003ch5\u003eWhat if I miss a dose?\u003c\/h5\u003e\n\u003cp\u003eTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\u003c\/p\u003e\n\n\u003ch5\u003eHow should I store this medication?\u003c\/h5\u003e\nStore at room temperature away from moisture and heat.\n\n\u003ch5\u003eWhat are the possible side effects of using this medication?\u003c\/h5\u003e\nGet emergency medical help if you have signs of an allergic reaction to apremilast: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\n\n\u003cul\u003e\n\u003cli\u003esevere diarrhea, nausea, and vomiting;\u003c\/li\u003e\n\u003cli\u003eunexplained weight loss, or if you lose a lot of weight;\u003c\/li\u003e\n\u003cli\u003emood changes, new or worsening depression; or\u003c\/li\u003e\n\u003cli\u003ethoughts of suicide or hurting yourself.\u003c\/li\u003e\n\u003cli\u003eCommon apremilast side effects may include:\u003c\/li\u003e\n\u003cli\u003enausea, diarrhea;\u003c\/li\u003e\n\u003cli\u003eheadache; or\u003c\/li\u003e\n\u003cli\u003ecold symptoms such as stuffy nose, sneezing, sore throat.\u003c\/li\u003e\n\u003c\/ul\u003e\n\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.","brand":"AdvocHealth","offers":[{"title":"30mg - 56 tab - Canada","offer_id":47192713986366,"sku":"","price":3198.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.advochealth.com\/products\/apremilast-apremilast","provider":"AdvocHealth","version":"1.0","type":"link"}