{"product_id":"elidel-pimecrolimus","title":"ELIDEL (Pimecrolimus)","description":"\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003ePimecrolimus, Elidel\u003c\/strong\u003e\u003cbr\u003eDescription: Calcineurin Inhibitor, Immunosuppressant\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“ALERT: US Boxed Warning\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAppropriate use:\u003c\/b\u003e\u003cspan\u003e  Long-term safety of topical calcineurin inhibitors has not been established. Continuous long-term use of topical calcineurin inhibitors, including pimecrolimus, in any age group should be avoided, and application limited to areas of involvement with atopic dermatitis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMalignancy:\u003c\/b\u003e\u003cspan\u003e Although a causal relationship has not been established, rare cases of malignancy (eg, skin malignancy, lymphoma) have been reported in patients treated with topical calcineurin inhibitors including pimecrolimus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePediatrics:\u003c\/b\u003e\u003cspan\u003e Pimecrolimus is not indicated for use in children younger than 2 years.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOfficially indicated for the treatment of atopic dermatitis.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003ePimecrolimus, Elidel when applied topically will bind to macrophilin-12 (FKBP-12) and inhibit calcium-dependent phosphatase, calcineurin.  As a consequence, Pimecrolimus, Elidel blocks cytokine transcription and inhibits T-cell activation which will reduce the body’s immunogenic response to atopic dermatitis.\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan\u003eAtopic Dermatitis\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTopical: Apply a thin layer to the affected area(s) twice daily.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eHow to Use Topical Pimecrolimus, Elidel:\u003c\/b\u003e  Apply a thin layer to the affected area twice daily.  Do not cover the areas with an occlusive dressing.  A local sensation of burning and redness is very commonly experienced during the first days to week when using Elidel\/Pimecrolimus.  Stop using when symptoms resolve and\/or re-evaluate if symptoms still persist beyond 6 weeks. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat should I watch for while using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003eHigher risk of developing \u003c\/span\u003e\u003cspan\u003eeczema herpeticum, varicella zoster, and herpes simplex\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAssociated with the development of lymphadenopathy, malignancy, skin papilloma\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDo not use in immunocompromised patients\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003eIf you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003eKeep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003eThe most common adverse effects include the following when using topical Elidel\/Pimecrolimus:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e10%:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCentral nervous system: Headache (children and adolescents 11% to 25%; adults 7%), fever (children and adolescents 13%; adults 1%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInfection: Influenza (3% to 13%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eLocal: Local burning (adults 26%; children and adolescents 2% to 8%; tends to resolve\/improve as lesions resolve), application site reaction (adults 15%; children and adolescents 2%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRespiratory: Nasopharyngitis (infants, children, and adolescents 10% to 27%; adults 8%), upper respiratory tract infection (children and adolescents 14% to 19%; adults 4%), cough (children and adolescents 9% to 16%; adults 2%), bronchitis (children and adolescents ≤11%; adults ≤2%)\u003c\/span\u003e\u003c\/p\u003e","brand":"VALEANT","offers":[{"title":"1% - 30g Cream - Canada - Brand","offer_id":47133889397054,"sku":null,"price":221.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/products\/BLOB_CREAM_18db9a03-47be-4e09-953c-07f7385243e4.jpg?v=1695126408","url":"https:\/\/www.advochealth.com\/products\/elidel-pimecrolimus","provider":"AdvocHealth","version":"1.0","type":"link"}