{"product_id":"enspryng-satralizumab","title":"ENSPRYNG (Satralizumab)","description":"\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cb\u003eENSPRYNG (Satralizumab)\u003cbr\u003e\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003eMonoclonal Antibody\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eENSPRYNG (Satralizumab) is indicated for the treatment of n\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003eeuromyelitis optica spectrum disorder.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eENSPRYNG (Satralizumab) is a humanized monoclonal antibody that binds to interleukin-6 (IL-6) receptors and inhibits IL-6 signalling pathways involved in inflammation.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cem\u003eSQ:\u003c\/em\u003e Loading dose: inject 120mg subcutaneously every 2 weeks for 3 doses (weeks 0, 2, and 4), followed by a maintenance dose of 120mg once every 4 weeks.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHow to Take:\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e Prior to using, remove the prefilled syringe and allow it to warm to room temperature. \u003c\/span\u003eAdminister the full amount in the prefilled syringe (1 mL). Administer subcutaneously into the abdomen or thigh. Rotate injection sites with each administration; avoid injecting into moles, scars, or tender, bruised, red, or hard skin.\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat should I watch for while using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eBefore starting ENSPRYNG (Satralizumab) make sure your physician is aware of any allergies or medications you currently take, and current medical conditions.  Satralizumab can cause elevated liver enzymes, neutropenia, hepatitis B reactivation when used in immunosuppressive therapies and tuberculosis in patients treated with other IL-6 receptor antagonists.  Immunization with live-attenuated or live vaccines should not be used during therapy.  Administer all live or live-attenuated vaccines at least 4 weeks prior, and non-live vaccines at least 2 weeks prior to treatment.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIf a starting dose is missed, take the missed dose immediately, then maintain the 2-week dosing interval from your new starting date until the first 3 doses are complete, and then continue with ongoing doses every 4 weeks.\u003c\/p\u003e\n\u003cp\u003eIf an ongoing dose is missed, \u003cspan data-mce-fragment=\"1\"\u003etake the missed dose\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e immediately\u003c\/span\u003e, then wait the 4-week interval from your new starting date, and continue with ongoing doses every 4 weeks.\u003c\/p\u003e\n\u003cp\u003eSpeak with your healthcare provider if you have any questions about how to restart treatment or if it has been more than 8 weeks since your last dose.\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003eStore in the refrigerator at 2º to 8ºC (36º to 46ºF), until ready to use. If unopened, ENSPRYNG (Satralizumab) can be removed from and returned to the refrigerator, if necessary. If stored at room temperature, the total combined time out of refrigeration should not exceed 8 days at a temperature that does not exceed 30°C.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSkin rash, gastritis, nausea, elevated liver enzymes, antibody development, infection, fatigue, headache, joint pain, pharyngitis, nasopharyngitis, upper respiratory tract infection, cellulitis, pruritis, diarrhea, injection size irritation, depression, and falling.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eNote this is not a complete list of side effects for ENSPRYNG (Satralizumab), only common ones.\u003c\/span\u003e\u003c\/p\u003e","brand":"HOFFMAN-LA ROCHE","offers":[{"title":"120mg\/ml - 1x1ml Prefilled Syringe - Canada","offer_id":47133896180030,"sku":null,"price":11340.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/products\/Enspryng.jpg?v=1695126459","url":"https:\/\/www.advochealth.com\/products\/enspryng-satralizumab","provider":"AdvocHealth","version":"1.0","type":"link"}