{"product_id":"eucrisa-crisaborole","title":"EUCRISA (Crisaborole)","description":"\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eEUCRISA (Crisaborole)\u003c\/strong\u003e\u003cbr\u003eTopical Phosphodiesterase-4-Enzyme Inhibitor\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eEUCRISA (Crisaborole) \u003c\/span\u003e\u003cspan\u003eis indicated for the treatment of atopic dermatitis.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003eEUCRISA (Crisaborole) is an inhibitor of phosphodiesterase 4 (PDE4) and works intracellularly to modulate a network of pro-inflammatory and anti-inflammatory mediators.  Phosphodiesterase 4 inhibition elevates intracellular cAMP levels, thereby reducing the inflammatory response by modulating the expression of tumor necrosis factor-α (TNF-α), interleukin-23 (IL-23), IL-17 and IL-10.\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cem\u003eTopical:\u003c\/em\u003e Apply a thin film to affected area(s) 2 times daily.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eHow to Take:\u003c\/b\u003e Wash your hands before and after applying each time.  For topical use only, do not apply to the eyes, eyelids, mouth, and\/or mucous membranes.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat should I watch for while using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003eDo not use if you experience any hypersensitivity reactions including contact urticaria, severe pruritus, swelling, or erythema (at the application site or at a distant site).\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003eIf you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003eKeep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eApplication site pain, u\u003c\/span\u003e\u003cspan\u003erticaria.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNote this is not a complete list of side effects for EUCRISA (Crisaborole), only common ones.\u003c\/span\u003e\u003c\/p\u003e","brand":"PFIZER","offers":[{"title":"2% - 60g Ointment - Canada","offer_id":47133890707774,"sku":null,"price":504.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/products\/BLOB_CREAM_04a01221-9864-46ec-8f03-3001ebcda348.jpg?v=1695126419","url":"https:\/\/www.advochealth.com\/products\/eucrisa-crisaborole","provider":"AdvocHealth","version":"1.0","type":"link"}