{"product_id":"norditropin-nordiflex-somatropin","title":"NORDITROPIN NORDIFLEX (Somatropin)","description":"\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eRecombinant Human Growth Hormone (Somatropin)\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/strong\u003eGrowth Hormone\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eBrand Name US:\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eGenotropin, Humatrope, Norditropin, Nutropin, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eBrand Name Canada:\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eGenotropin, Humatrope, Norditropin, Nutropin, Omnitrope, Saizen, Serostim\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eNORDITROPIN (Somatropin) is indicated for treatment of growth failure, growth hormone deficiency, HIV-associated wasting, short bowel syndrome.\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eNORDITROPIN (Somatropin) is a purified polypeptide hormone of recombinant DNA origin which contains the same amino acid sequence as human growth hormone.  Human growth hormone is produced by the pituitary and binds to GH receptors on multiple different tissues in the body.  Human growth hormone is an anabolic hormone that promotes linear bone growth, protein synthesis in skeletal muscle.  Human growth hormone assists in partitioning nutrients towards anabolism by increasing lipolysis and decreasing lipogenesis while decreasing glucose intake and increasing hepatic glucose output through receptor upregulation and downregulation.  Human growth hormone also stimulates erythropoietin which increases red blood cell mass; exerts both insulin-like and diabetogenic effects; enhances the transmucosal transport of water, electrolytes, and nutrients across the gut.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cem data-mce-fragment=\"1\"\u003eSQ:\u003c\/em\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eInject an initial dose of 0.04mg\/kg\/week\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003esubcutaneously\u003c\/span\u003e; dose can be increased at 4 and 8 week intervals to a maximum of 0.08mg\/kg\/week.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eHow to Take: \u003c\/b\u003eNever shake the vial, prefilled pen, cartridge.  Administer the injection subcutaneously and rotate the injection sites (back of upper arm, abdomen, buttock, or thigh) to avoid tissue atrophy.  Always use the dose prescribed and adjust the dose based on individual requirements to minimize adverse events.  For weight-based dosing, obese patients are more likely to experience adverse effects when treated with a weight-based regimen.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat should I watch for while using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eNORDITROPIN\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e(Somatropin) can cause transient fluid retention, use with caution in arthralgia, myalgia, nerve compression syndromes. \u003cspan data-mce-fragment=\"1\"\u003eSomatropin c\u003c\/span\u003ean also decrease insulin sensitivity and exacerbate type 2 diabetes mellitus. Use with caution in patients with intracranial hypertension. Do not use in patients with an active neoplasm, critical illness.\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eTake the missed dose as soon as possible. If it is almost time for the next scheduled dose, do not use extra medicine to make up for the missed dose.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eBefore use, keep NORDITROPIN (Somatropin) cartridges and loaded pens in the refrigerator between 36°F and 46°F (2°C and 8°C). Once a cartridge has been loaded into the pen, it should not be removed until it is empty or 28 days have passed since its first use. To protect medicine from light, keep cartridges in their original packaging until a cartridge is loaded into the pen. Do not freeze.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePeripheral edema, facial edema, edema, lower extremity edema, pain, hypoesthesia, headache, paresthesia, hypothyroidism, elevated glycosylated hemoglobin, eosinophilia, nausea, flatulence, abdominal pain, vomiting, antibody development, infection, pain at injection site, injection site reaction, arthralgia, arthropathy, myalgia, scoliosis, limb pain, swelling of extremities, ostealgia, otitis media, upper respiratory tract infection.\u003cspan data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eNote this is not a complete list of side effects for NORDITROPIN (Somatropin), only common ones.\u003c\/span\u003e\u003c\/p\u003e","brand":"NOVO NORDISK","offers":[{"title":"5mg - 1x1.5ml Prefilled Pen - Canada","offer_id":47161479430462,"sku":"","price":560.0,"currency_code":"USD","in_stock":true},{"title":"10mg - 1x1.5ml Prefilled Pen - Canada","offer_id":47161449349438,"sku":"","price":1035.0,"currency_code":"USD","in_stock":true},{"title":"15mg - 1x1.5ml Prefilled Pen - Canada","offer_id":47161449414974,"sku":"","price":1750.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/products\/Nordiflex5.jpg?v=1695301121","url":"https:\/\/www.advochealth.com\/products\/norditropin-nordiflex-somatropin","provider":"AdvocHealth","version":"1.0","type":"link"}