{"product_id":"ozempic-semaglutide","title":"OZEMPIC (Semaglutide)","description":"\u003ch5 style=\"margin: 0px 0px 0.66rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong\u003eOZEMPIC (Semaglutide)\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eAntidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eOZEMPIC (Semaglutide) is officially indicated for the treatment of Diabetes mellitus type 2.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eALERT: WARNING\u003cbr\u003e\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\"\u003eIn rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. It is unknown whether semaglutide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSemaglutide is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Counsel patients regarding the potential risk for MTC with the use of semaglutide and inform them of symptoms of thyroid tumors (eg, a mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with semaglutide.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 style=\"margin: 0px 0px 0.66rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003eOZEMPIC (Semaglutide) is a long-acting analog of human glucagon-like peptide-1 (GLP-1) (an incretin hormone).  Semaglutide works in multiple of ways to lower blood glucose and hemoglobin A1C.  It stimulates the beta cells of the pancreas to release insulin when blood glucose levels are high, it slows down gastric emptying, the rate at which glucose enters the blood after meals, and also helps lower hepatic glucose output by suppressing pancreatic glucagon secretion.\u003c\/p\u003e\n\u003ch5 style=\"margin: 0px 0px 0.66rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSQ:\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\"\u003e Inject 0.25 mg subcutaneously once weekly for 4 weeks, then increase to 0.5 mg once weekly for 4 weeks, then increase to 1 mg once weekly if needed to reach target blood sugar. The lower initial dose of 0.25 mg weekly is intended to reduce gastric side effects but is not enough have any effect on blood sugar. If changing the day of administration is necessary, allow at least 48 hours between 2 doses. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 style=\"margin: 0px 0px 0.66rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat should I watch for while using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eBefore starting OZEMPIC (Semaglutide), make sure your physician is aware of any allergies, medications you currently take, if you have a history of bariatric surgery, diabetic retinopathy, gallbladder disease, kidney disease, a history of pancreatitis, are pregnant, or breastfeeding.  If you suspect pancreatitis, discontinue immediately.  Diabetic retinopathy has  been reported and should be closely monitored in patients with a history of diabetic retinopathy.  Hypoglycemia can occur when\u003cspan\u003e \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eSemaglutide\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eis combined with an insulin secretagogue or insulin. Monitor renal function in patients with renal impairment reporting severe adverse gastrointestinal reactions.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 style=\"margin: 0px 0px 0.66rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan\u003eIf a dosage is missed, then it should be administered as soon as possible if there is at least 48 hours before the next planned dosage. If there is less than 48 hours until your next dose, skip the missed dose. Continue with originally scheduled dosing schedule moving forward in either scenario.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 style=\"margin: 0px 0px 0.66rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\" data-mce-fragment=\"1\"\u003eKeep\u003cspan\u003e \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003erefrigerated until the first time you use it. You should keep it in the refrigerator (between 36°F to 46°F or 2°C to 8°C) when it’s new and unused.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003eAfter you’ve used your pen for the first time, you can either store your pen for 56 days at room temperature (between 59ºF to 86ºF or 15ºC to 30ºC) or you can still keep it in the refrigerator for 56 days. Keep the pen cap on when it is not in use.\u003c\/p\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003eDon’t freeze the pen or use it if it has been frozen. Be sure to store it out of reach of children and pets. Throw away pen after 56 days (whether kept in the refrigerator or at room temperature), even if it still has product left in it. Write the disposal date on your calendar so you can keep track.\u003c\/p\u003e\n\u003ch5 style=\"margin: 0px 0px 0.66rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp style=\"margin: 0px 0px 1rem; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003eWell tolerated, most side effects are transient and mild to moderate in nature.  The most common side effects include increased levels of amylase (digests starch), gastrointestinal effects (diarrhea\/gas\/boating), increased serum lipase (digests fats), nausea, and abdominal pain.\u003c\/p\u003e\n\u003cp style=\"margin: 0px; color: #1f2124; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\" data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eNote this is not a complete list of side effects for\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eOZEMPIC (Semaglutide),\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eonly common ones.\u003c\/span\u003e\u003c\/p\u003e","brand":"NOVO NORDISK","offers":[{"title":"1mg - 1x4mg (4mg\/3mL) Prefilled Pen - Canada - may not be available until after 10\/21\/23.","offer_id":47369888956734,"sku":"","price":655.0,"currency_code":"USD","in_stock":true},{"title":"0.25mg\/0.5mg - 1x2mg Prefilled Pen - Canada","offer_id":45324958236990,"sku":"","price":655.0,"currency_code":"USD","in_stock":true},{"title":"8mg\/3mL - 1 Pre-Filled Pen  - Canada - Diabetes diagnosis is needed for this strength","offer_id":47370844045630,"sku":"","price":655.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/files\/ozempic-ehr-blue.png?v=1685118118","url":"https:\/\/www.advochealth.com\/products\/ozempic-semaglutide","provider":"AdvocHealth","version":"1.0","type":"link"}