{"product_id":"verzenio-abemaciclib","title":"VERZENIO (Abemaciclib)","description":"\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong\u003eVERZENIO (Abemaciclib)\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eAntineoplastic, Cyclin-Dependent Kinase Inhibitor\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan mce-data-marked=\"1\" data-mce-fragment=\"1\"\u003eVERZENIO (Abemaciclib) is indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan\u003eVERZENIO (Abemaciclib) contain cyclin-dependent kinases (CDK) 4 and 6 inhibitors which inhibit the growth of cancer cells by disrupting their cell cycle, resulting in the arrest at the G1 phase. Abemaciclib can be used either alone or in combination with antiestrogens to reduce tumor size.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cem\u003eOral: \u003c\/em\u003eWhen used as a single agent, the recommended dose is 200 mg taken orally twice daily.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong\u003eHow to Take\u003c\/strong\u003e\u003cspan\u003e: Can be taken with or without food.  Make sure to swallow whole, do not crush, split or chew tablets (never ingest tablets that are broken, cracked, or not fully intact).\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan\u003e\u003cspan style=\"font-weight: 400;\"\u003eDiscontinue VERZENIO (Abemaciclib) for patients unable to tolerate 50 mg twice daily.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat should I watch for while using this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eBefore starting on \u003cspan data-mce-fragment=\"1\"\u003eVERZENIO (Abemaciclib),\u003c\/span\u003e you should know that it may affect your fertility. This may affect your ability to father a child. Low white blood cell counts are common while taking \u003cspan data-mce-fragment=\"1\"\u003eAbemaciclib\u003c\/span\u003e. They may cause serious infections that can cause death. \u003cspan data-mce-fragment=\"1\"\u003eAbemaciclib\u003c\/span\u003e can cause serious liver problem.  \u003cspan data-mce-fragment=\"1\"\u003eAbemaciclib\u003c\/span\u003e can cause severe inflammation of the lungs during treatment that can lead to death.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eIf you \u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003evomit or miss a dose\u003c\/span\u003e, continue to \u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003etake the prescribed dose at the next scheduled time\u003c\/span\u003e. Do not take 2 doses at the same time to make up for the missed dose.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eKeep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDiarrhea, nausea, vomiting, decreased appetite, bloating, abdominal pain, headache, dizziness, vertigo, hair loss, muscle weakness, fatigue, bone fracture, rash, dry skin, infected or darkened or painful skin, bruising, inflamed fat layer below the skin, palmar-plantar erythrodysesthesia syndrome, increased tears, eye pain and blurred vision, changes to your sense of taste, dry mouth, sores in mouth, difficulty swallowing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan\u003eNote this is not a complete list of side effects for VERZENIO (Abemaciclib), only common ones.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"ELI LILLY","offers":[{"title":"50mg - 28 Tab - Canada - SPECIAL ORDER","offer_id":47160631230782,"sku":null,"price":4887.0,"currency_code":"USD","in_stock":true},{"title":"100mg - 28 Tab - Canada - SPECIAL ORDER","offer_id":47160631263550,"sku":null,"price":4887.0,"currency_code":"USD","in_stock":true},{"title":"150mg - 28 Tab - Canada - SPECIAL ORDER","offer_id":47160631296318,"sku":null,"price":4887.0,"currency_code":"USD","in_stock":true},{"title":"200mg - 28 Tab - Canada - SPECIAL ORDER","offer_id":47160631329086,"sku":null,"price":4887.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/products\/Verzenio50.png?v=1695298088","url":"https:\/\/www.advochealth.com\/products\/verzenio-abemaciclib","provider":"AdvocHealth","version":"1.0","type":"link"}