{"product_id":"wakix-pitolisant","title":"WAKIX (Pitolisant)","description":"\u003ch5\u003eWhat is this medication?\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e tablets are used to treat adults with excessive daytime sleepiness (EDS) or cataplexy (sudden loss of muscle strength) both are symptoms of narcolepsy, which is a long-term sleep disorder.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e is thought to work by changing the amount of histamine in the area of the brain that controls sleep and wakefulness, as it acts on the histamine-3 (H3) receptor.\u003c\/p\u003e\n\u003cp\u003eNarcolepsy is a disorder that affects how well the brain control sleep-wake cycles. Often people with narcolepsy have interrupted sleep and may feel very sleepy during the day, which interferes with their life. Everyone that has narcolepsy has excessive daytime sleepiness, which is when they have an overwhelming sense of sleepiness that comes on quickly.\u003c\/p\u003e\n\u003cp\u003eCataplexy is when you have a sudden loss of muscle tone while you are awake, which leads to muscle weakness and loss of muscle control. Cataplexy can be mild and only last a short time, or it can be severe with a full body collapse.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e is the only FDA-approved medicine for narcolepsy medicine that is not a controlled substance treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e is not a stimulant medicine.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003cp\u003eYou should not use \u003cstrong\u003eWakix\u003c\/strong\u003e if you have severe liver disease.\u003c\/p\u003e\n\u003ch5\u003eHow should I use this medication?\u003c\/h5\u003e\n\u003cp\u003eTake \u003cstrong\u003eWakix\u003c\/strong\u003e exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e tablet is usually taken once daily when you wake up, it can be taken with or without food.\u003c\/p\u003e\n\u003cp\u003eYour doctor will probably start you on a low dose and gradually increase your dose, not more than once every 7 days.\u003c\/p\u003e\n\u003cp\u003eIt may take up to 8 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDosing information:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe recommended dosage range for \u003cstrong\u003eWakix\u003c\/strong\u003e is 17.8 mg to 35.6 mg taken once daily in the morning upon wakening.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eThe dosage should be increased gradually as follows:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eWeek 1\u003c\/strong\u003e\u003c\/span\u003e: Start with a dosage of 8.9 mg (two 4.45 mg tablets) once daily\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan style=\"text-decoration: underline;\"\u003eWeek 2\u003c\/span\u003e\u003c\/strong\u003e: Increase dosage to 17.8 mg (one 17.8 mg tablet) once daily\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eWeek 3\u003c\/strong\u003e\u003c\/span\u003e: Dose may increase to the maximum recommended dosage of 35.6 mg (two 17.8 mg tablets) once daily\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNote: Dose may be adjusted based on tolerability.\u003c\/p\u003e\n\u003cp\u003eIt may take up to 8 weeks for some patients to achieve a clinical response.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e is supplied as an oral tablet containing 4.45 mg or 17.8 mg of pitolisant.\u003c\/p\u003e\n\u003ch5\u003eWhat if I miss a dose?\u003c\/h5\u003e\n\u003cp\u003eSkip the missed dose and use your next dose the following morning at the regular time. Do not use two doses at one time.\u003c\/p\u003e\n\u003ch5\u003eHow should I store this medication?\u003c\/h5\u003e\n\u003cp\u003eStore at 20° C to 25° C (68° F to 77°F); excursions permitted between 15° C to 30° C (59° F to 86° F)\u003c\/p\u003e\n\u003ch5\u003eWhat should I avoid while taking Wakix?\u003c\/h5\u003e\n\u003cp\u003eFollow your doctor's instructions about any restrictions on food, beverages, or activity.\u003c\/p\u003e\n\u003ch5\u003eWhat are the possible side effects of using this medication?\u003c\/h5\u003e\n\u003cp\u003eGet emergency medical help if you have signs of an allergic reaction:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ehives;\u003c\/li\u003e\n\u003cli\u003edifficulty breathing;\u003c\/li\u003e\n\u003cli\u003eswelling of your face, lips, tongue, or throat.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e may cause serious side effects.\u003c\/p\u003e\n\u003cp\u003eCall your doctor at once if you have:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003efast or pounding heartbeats;, fluttering in your chest;\u003c\/li\u003e\n\u003cli\u003eshortness of breath; or\u003c\/li\u003e\n\u003cli\u003esudden dizziness (like you might pass out).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCommon side effects of \u003cstrong\u003eWakix\u003c\/strong\u003e may include\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003enausea;\u003c\/li\u003e\n\u003cli\u003eanxiety; or\u003c\/li\u003e\n\u003cli\u003esleep problems (insomnia).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\u003c\/p\u003e\n\u003ch5\u003eWhat other drugs will affect Wakix?\u003c\/h5\u003e\n\u003cp\u003eWhen you start or stop taking this medicine, your doctor may need to adjust the doses of any other medicines you take on a regular basis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWakix\u003c\/strong\u003e can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.\u003c\/p\u003e\n\u003cp\u003eOther drugs may affect pitolisant, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\u003c\/p\u003e\n\u003cp\u003eTo check for interactions with \u003cstrong\u003eWakix\u003c\/strong\u003e click on the link below.\u003c\/p\u003e","brand":"ENDO VENTURES LTD.","offers":[{"title":"5mg - 30 Tab - Canada","offer_id":47267569434942,"sku":"","price":2450.0,"currency_code":"USD","in_stock":true},{"title":"20mg - 30 Tab - Canada","offer_id":47267569598782,"sku":"","price":2450.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.advochealth.com\/products\/wakix-pitolisant","provider":"AdvocHealth","version":"1.0","type":"link"}