{"product_id":"wellbutrin-xl-bupropion","title":"WELLBUTRIN XL (Bupropion)","description":"\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat is this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eBupropion, Wellbutrin\u003c\/strong\u003e\u003cbr\u003eDopamine\/Norepinephrine Reuptake Inhibitor\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBupropion is officially indicated for major depressive disorder, smoking cessation, and seasonal affective disorder depending on which dosage form is used.  It is also prescribed off-label for ADHD and in combination for SSRI-induced sexual dysfunction.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“ALERT: US Boxed Warning\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSuicidality and antidepressant drugs:\u003cbr\u003e\u003c\/b\u003eAntidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials. These trials did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in subjects aged 65 and older.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn patients of all ages who are started on antidepressant therapy, monitor closely for worsening and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber. Bupropion is not approved for use in pediatric patients.”\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow does this medication work? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan\u003eWellbutrin\/Bupropion appears to enhance norepinephrine and dopamine activity and does not inhibit monoamine oxidase or the reuptake of serotonin like other antidepressants.   Selective serotonin reuptake inhibitors (SSRIs) can interfere with different aspects of sexual functioning, including desire, arousal, and orgasm.  Treatment options include either switching to a different antidepressant or augmenting therapy with bupropion which can counter the effects of SSRI-induced sexual dysfunction.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I take this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003eSSRI-induced sexual dysfunction, augmentation (off-label use)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e12-hour extended release (sustained release): 150mg once daily for the first 3 days then increased dose to 150mg twice daily based on response and tolerability.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHow to Take Bupropion, Wellbutrin XL\/SR:\u003cspan\u003e \u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003eDo not split the tablet; take the entire tablet and swallow whole.  If you are taking only one dose per day, take it in the morning.  If you take two doses per day, take once in the morning and one in the afternoon, at least 8 hours apart.  Avoid taking at bedtime to prevent insomnia.  Take with food if you have any problems with nausea or an upset stomach. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eWhat should I watch for while using this medication?\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003eDo not use in patients with hypersensitivity to bupropion; seizure disorders; current or prior diagnosis of severe anorexia nervosa and\/or bulimia (due to risk of seizures).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDo not use on conjunction with monoamine oxidase inhibitors\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUse with caution in patients with risk factors predisposing them to seizures such as head trauma, brain tumor, concurrent medications which lower the seizure threshold, abrupt withdrawal from alcohol, benzodiazepines or barbiturates, abuse of stimulant drugs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eYou Need to Avoid Bupropion, Wellbutrin XL\/SR:\u003c\/b\u003e\u003cspan\u003e Do not use it if you have an eating disorder such as bulimia or anorexia nervosa due to the inherent higher risk of seizures.  \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContact Your Doctor if You Ever Experience:\u003c\/b\u003e\u003cspan\u003e Stop taking this medication and contact your doctor if you experience a rash (particularly in combination with facial swelling, breathing difficulties or flu-like symptoms); severe agitation, anxiety or excitation, major sleep disturbance or unusual mood change, muscle twitching or convulsions.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat if I miss a dose?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eIf you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow should I store this medication?\u003c\/span\u003e\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eKeep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5 data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWhat are the possible side effects of using this medication? \u003c\/span\u003e\u003c\/h5\u003e\n\u003cp\u003e\u003cspan\u003eWell tolerated, most side effects are transient and mild to moderate in nature.  The most common side effects include:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt;10%\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eCardiovascular:\u003c\/em\u003e Tachycardia (\u0026lt;11%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eCentral Nervous System:\u003c\/em\u003e Insomnia (11% to 40%), headache (25% to 34%), agitation (2% to 32%), dizziness (6% to 22%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eDermatologic:\u003c\/em\u003e Diaphoresis (5% to 22%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eEndocrine and Metabolic:\u003c\/em\u003e Weight loss (14% to 23%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eGastrointestinal:\u003c\/em\u003e Xerostomia (10% to 28%), constipation (8% to 26%), nausea and vomiting (23%), nausea (1% to 18%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eNeuromuscular and Skeletal:\u003c\/em\u003e Tremor (1% to 21%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eOphthalmic:\u003c\/em\u003e Blurred vision (3% to 15%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003eRespiratory:\u003c\/em\u003e Nasopharyngitis (13%), pharyngitis (3% to 13%), rhinitis (12%)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eNote this is not a complete list of side effects, only common ones\u003c\/span\u003e\u003c\/p\u003e","brand":"VALEANT","offers":[{"title":"150mg - 90 Tab - Canada","offer_id":47160891179326,"sku":null,"price":3759.0,"currency_code":"USD","in_stock":true},{"title":"300mg - 90 Tab - Canada","offer_id":47160891277630,"sku":null,"price":3759.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0711\/0321\/7982\/products\/Wellbutrin150mg.jpg?v=1695299168","url":"https:\/\/www.advochealth.com\/products\/wellbutrin-xl-bupropion","provider":"AdvocHealth","version":"1.0","type":"link"}